The tryptophan operon in E. coli consists of
these five genes and their regulating sequences.
The latter include promoter and operator, a
leader sequence, and attenuator sequences.
Translation of the five structural genes results
from a continuous trp operon mRNA. In this,
leader sequences coded for by L-sequence
genes are connected in series. The attenuator
sequences are part of the L-sequences. When
tryptophan is present in the medium, translation
of trp leader RNA is discontinued in the region
of an attenuator sequence, before reaching
the first structural gene.
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